Guess What? I've decided to do just that.
OK, well. I wasn't exactly sure how I was to go about this. I talked it over with other quilters and have decided to start by tracing the piece of art onto piece of muslin.
Now that I have that traced I will start looking through my stash to find the solids that I will need to applique the shapes onto the muslin. The challenge will be the quilting. I want to try to re-create the brushwork by free motion quilting.